Differential Scanning Calorimetry (DSC) – the analytical technique used to measure the enthalpy changes in the sample due to changes in its physical and chemical properties as a function of temperature or time.

Application of the DSC method:

  • first- and second-order phase transitions studies
    •  melting point
    •  crystallization
    •  solid-solid phase transition
    •  glass transition
  • chemical reactions studies with heat emission or with heat absorption including:
    •  thermal decomposition
    •  dissociation
    •  polymerization

We offer a thermal analysis for the various sample using Mettler Toledo DSC 822e calorimeter including:

  • determination of melting point
  • determination of glass transition temperature
  • studies on the polymorphism and pseudopolymorphism of pharmaceuticals substances
  • phase diagram study
  • purity determination

Technical data and accessories of Mettler Toledo 822e differential scanning calorimeter:

  • temperature range: – 65°C to 500°C
  • heating rate: 0.01 to 20°C/min
  • temperature accuracy: ± 0.2°C
  • resolution: 0.04 µW
  • sample size: min. 2 mg
  • intra cooler: Huber TC 100